| Comparison | Studies (RCTs) | Participants | Certainty | Effect |
|---|---|---|---|---|
| Nicotine vape vs NRT | ~12 RCTs | ~3,500 | HIGH | +4 per 100 |
| Nicotine vape vs non-nicotine vape | ~7 RCTs | ~2,100 | HIGH | +2 per 100 |
| Nicotine vape vs no support | ~15 RCTs | ~4,200 | MODERATE | +5 per 100 (est.) |
| Nicotine vape vs behavioral support | ~9 RCTs | ~2,800 | MODERATE | +3 per 100 (est.) |
| Adverse events (vape vs NRT) | ~20 studies | ~8,000 | MODERATE | No significant difference |
Numbers are approximate, derived from the Cochrane review's pooled analyses. "High" certainty means further research is very unlikely to change the estimate; "Moderate" means further research may have an important impact.
