The FDA's draft guidance, published March 11, 2026, represents the most significant shift in flavored e-cigarette regulation since the PMTA process began. For the first time, the FDA has created a formal framework that distinguishes between "lower-risk" flavors (menthol, mint, coffee, tea, spices, wintergreen) and "higher-risk" flavors (fruit, candy, dessert) — and sets different evidentiary standards for each. Then on May 5, the FDA authorized the Glas G2 device with Gold (mango) and Sapphire (blueberry) pods — the first non-tobacco, non-menthol flavored ENDS products ever approved, made possible by built-in device access restriction (DAR) technology that ties the device to a verified adult user's smartphone.

For the complete list of all 48 FDA-authorized products, see our complete FDA-authorized vape product list. For how the FDA's broader enforcement crackdown affects the market, read our FDA seize-and-destroy law guide.