- Nicotine delays sleep onset by 10–30 minutes and reduces total sleep time, with evening use having the strongest effect HIGH CONFIDENCE
- REM sleep is suppressed by 15–30% in nicotine users, affecting dreaming, memory consolidation, and emotional regulation HIGH CONFIDENCE
- Evening vapers have 2–3x higher insomnia risk compared to non-users or morning-only vapers MODERATE CONFIDENCE
- Sleep gets worse before it gets better after quitting — 1–3 weeks of withdrawal insomnia, then gradual improvement over 3–6 months MODERATE CONFIDENCE
- Nicotine-free vapes have minimal sleep impact for most people, though PG/VG vapor may cause mild throat irritation in sensitive individuals LOW CONFIDENCE
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